# GHRP-2 and GHRP-6

GHRP-2 (also called pralmorelin) and GHRP-6 are two lab-made peptides, each a short chain of six amino acids. Both act on the body's ghrelin receptor and prompt the release of growth hormone. This hub explains them in plain English, using journal papers, a Japanese drug label, regulator records and sport rules. It also says clearly where no human study exists.

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| --- | --- |
| Common names | GHRP-2 (pralmorelin) and GHRP-6 |
| Class | Growth hormone secretagogues: synthetic hexapeptides (six amino acids each) that act at the ghrelin receptor |
| GHRP-6 sequence | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 ([Bowers et al., 1992](https://pubmed.ncbi.nlm.nih.gov/1730807/)) |
| GHRP-2 sequence | Not taken from an opened paper for this hub, so it is not printed here |
| GHRP-6 serum half-life in men | 20 minutes for immunoreactive GHRP (Bowers et al., 1992) |
| Pralmorelin terminal half-life, 18 healthy men | About 0.42 to 0.69 hours after intravenous administration ([Japanese prescribing information, revised July 2022](https://s3-ap-northeast-1.amazonaws.com/medley-medicine/prescriptionpdf/200022_7223407D1027_1_08.pdf)) |
| Approved use of pralmorelin | A diagnostic for growth hormone secretion failure in Japan; sales began February 2005 (Japanese prescribing information) |
| Poisons Standard, October 2026 | Individual Schedule 4 entries for both, each also in Appendix D, clause 5 ([F2026L01327](https://www.legislation.gov.au/F2026L01327/latest/text)) |
| FDA 503B bulks list | Category 2: GHRP-2 (two named routes) and GHRP-6 ([FDA list, updated 21 March 2025](https://www.fda.gov/media/94164/download)) |
| WADA 2026 Prohibited List | Named at S2.2.4; prohibited at all times |

## Articles in this hub

- [GHRP-2 and GHRP-6 side effects: what the Japanese label, the FDA and the TGA record](https://www.formlaboratories.com/learn/ghrp-2-and-ghrp-6/ghrp-side-effects) - What is recorded about GHRP-2 (pralmorelin) and GHRP-6 safety: the Japanese diagnostic label's adverse reactions and class warning, the FDA 503B category 2 listing, and the gaps. Records only; not medical advice.
- [GHRP-2 and GHRP-6 study findings: what the research measured, and what it did not](https://www.formlaboratories.com/learn/ghrp-2-and-ghrp-6/ghrp-study-findings) - What human studies of GHRP-2 (pralmorelin) and GHRP-6 measured: growth hormone release, a Japanese diagnostic approval and a one-volunteer urine study. No body-composition outcome trial was opened.
- [How do GHRP-2 and GHRP-6 work? The ghrelin receptor and what the studies measured](https://www.formlaboratories.com/learn/ghrp-2-and-ghrp-6/how-ghrp-works) - How GHRP-2 and GHRP-6 act on the ghrelin receptor to release growth hormone, what Bowers and colleagues measured in 1992, the 20-minute GHRP-6 half-life, and the pralmorelin half-life range from the Japanese label.
- [Is GHRP-6 legal in Australia? Poisons Standard, TGA, FDA and WADA records for GHRP-2 and GHRP-6](https://www.formlaboratories.com/learn/ghrp-2-and-ghrp-6/is-ghrp-legal-in-australia) - What the October 2026 Poisons Standard, the TGA, the FDA and WADA record about GHRP-2 (pralmorelin) and GHRP-6, with sources and check dates. Records only; this is not legal advice.
- [What are GHRP-2 and GHRP-6? Two growth hormone secretagogues explained](https://www.formlaboratories.com/learn/ghrp-2-and-ghrp-6/what-is-ghrp) - What GHRP-2 (pralmorelin) and GHRP-6 are: synthetic six-amino-acid peptides that act on the ghrelin receptor, and how they differ from growth hormone and from growth hormone-releasing hormone.

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