Compound hub
Semax
Semax is a synthetic seven-amino-acid peptide modelled on a fragment of the hormone ACTH, and it is a registered drug in Russia according to the FDA's July 2026 review; no FDA-approved drug contains it. This hub collects the questions people ask about Semax and answers each from published studies and regulator records.
Record card
| Common name | Semax |
|---|---|
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro, seven amino acids (FDA briefing document, July 2026) |
| Formula and weight | C37H51N9O10S; 813.93 g/mol (FDA briefing document, July 2026) |
| CAS (free base) | 80714-61-0 (FDA briefing document, July 2026) |
| Origin | Synthetic analogue of the ACTH(4-10) fragment, developed in Russia (Deigin et al., Pharmaceutics, 2022) |
| Australian status as of 14 October 2026 | No individual entry in the October 2026 Poisons Standard (text search) |
| FDA status | Not a component of any FDA-approved drug (FDA briefing document, July 2026) |
| Registered medicine | Russia: 0.1% and 1% nasal drops (FDA briefing document, July 2026) |
Questions answered here
05- Is Semax legal? Australian, US and Russian statusSemax legal status: a text search of the October 2026 Poisons Standard found no entry naming Semax. What the TGA advisory, the FDA's July 2026 review, Russian registration and the WADA 2026 List record, with check dates and links.Updated 2026-10-14
- Semax half-life: what do studies say about how long it lasts?The FDA's July 2026 briefing document says its staff did not find a human pharmacokinetic study of Semax. What rat and test-tube studies measured, what the sources read did not report, and what is not known about N-acetyl Semax amidate.Updated 2026-10-14
- Semax side effects: what do studies and regulators record?Recorded safety data for Semax: the FDA's July 2026 review, one adverse-event report, human studies by size and population, the animal toxicity studies the FDA did not identify and what is unknown about N-acetyl Semax amidate.Updated 2026-10-14
- Does Semax work? What published studies of Semax foundQuestions about whether Semax works, answered from named studies and regulator documents: cell and rat findings on BDNF, small Russian human studies and the FDA's July 2026 briefing document. Each result is listed with its model, size and limit.Updated 2026-10-14
- Semax vs Adamax, N-acetyl Semax amidate and Dihexa: what is the difference?Semax compared with Adamax, N-acetyl Semax amidate and Dihexa: what each name refers to, what is published about each, and what the sources searched on 14 October 2026 did not find compared. Research material is not a medicine.Updated 2026-10-14
Form Laboratories supplies research-use-only reference material. Everything in this hub is an educational summary of published third-party literature. It is not medical advice, not a use instruction, and research material is not for human or animal use.