For laboratory research use only - not for human consumption
Third-party tested every lot
Batch paperwork included
Cold-chain dispatch
30-day documented-purity guarantee

About this compound

What is MOTS-C?

MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded by a short open reading frame within mitochondrial 12S rRNA.

The commonly cited sequence is MRWQEMGYIFYPRKLR.

The current page keeps MOTS-C in cellular, preclinical, and observational research context.

Specifications

The full label, set as a spec sheet.

This spec sheet is for identity and paperwork only. It lists the MT-RNR1 context, sequence, public database identifiers, and COA-led lot details for the 10 mg vial.

CompoundMOTS-C
Full nameMitochondrial ORF of the 12S rRNA type-c
Gene contextMT-RNR1 short open reading frame
SequenceMRWQEMGYIFYPRKLR
Length16 amino acids
CAS1627580-64-6 (database/catalog identifier)
Molecular formulaC101H152N28O22S2
Molecular weight2174.6 g/mol
LotMOT-2506

Research background

What MOTS-C studies look at

The 2015 Cell Metabolism paper describes MOTS-C as a 16-amino-acid mitochondrial-derived peptide encoded in mitochondrial 12S rRNA.

Later papers look at AMPK-linked signalling, movement into the nucleus during metabolic stress, gene-expression response, GLUT4 context, mitofusion dependence, and CK2 binding in model systems.

Because this area often sits near age, exercise, and metabolism topics, the page keeps MOTS-C in cellular, preclinical, and observational research context.

Areas of active research

Where MOTS-C sits in research literature.

These notes describe study context only. They are not human-use or veterinary-use instructions.

Mitochondrial identity

Shows the MT-RNR1 short-ORF context and the MRWQEMGYIFYPRKLR sequence in the spec sheet.

Single 10 mg vial

MOTS-C is listed as one 10 mg research vial, with the product code and lot kept visible.

COA-led details

Appearance and release information stay tied to the COA and lot paperwork, not guessed from papers.

Lab-only guardrail

Keeps age, exercise, and metabolism papers in model context, with research use only framing intact.

Selected references

2015 discovery paperLee C et al. Cell Metab. 2015;21(3):443-454.

2018 stress-response paperKim KH et al. Cell Metab. 2018;28(3):516-524.e7.

2024 CK2 paperKumagai H et al. iScience. 2024;27(11):111212.

Research library

Read the full MOTS-C research guide.

A plain guide to MOTS-C identity, MT-RNR1 context, cellular stress signalling, and the limits of the available papers.

Learn more about MOTS-C

This summary is for scientific and educational context only. It is not preparation guidance, administration guidance, or a statement about use in people or animals.

Verification

Lot paperwork before checkout.

The certificate panel keeps purity, lot, identity, appearance, and release state visible beside the buy controls.

0.0%

Current displayed purity for this product page.

Certificate of AnalysisCOA-MOT-2506
HPLC chromatogramMethod file
Batch recordTrace file
Storage note2-8 C
Certificate of Analysis
CompoundMOTS-C
LotMOT-2506
Purity (HPLC)98.0%
IdentityCOA check
AppearanceLyophilized powder
ReleasedPending final batch release
Third-party verification modelREF MOT-2506
Form Laboratories cold-chain packaging kit

Storage and shipping

Packed for a controlled handoff.

01

Cold-chain packing

Packed with temperature-aware handoff notes and protective outer packaging.

02

Label-led storage

Storage conditions stay on the vial, packing slip, and COA paperwork.

03

Light protection

Outer packaging is selected to reduce heat and light exposure before lab storage.

01

Invoice checkout

Checkout gathers order details before bank-transfer information is issued.

02

COA in the box

Each lot has matching certificate paperwork for review before lab intake.

03

Lot lookup support

Support starts with the printed lot code, vial label, and matching COA.

04

Discreet packaging

Plain outer packaging keeps shipment information quiet and practical.

FAQ

Questions, answered plainly.

MOTS-C is supplied as laboratory research material only. It is 18+ only, not for human consumption, and not for veterinary use.

Precision peptides for advanced research

Keep the lot details visible.

MOTS-C is presented with size, purity, storage, COA, and research-use-only language visible before purchase.Browse the series
2026 Form Laboratories - Research use onlyAustralia - lot-matched paperwork