Compound hub
Tirzepatide
Tirzepatide (LY3298176) is a synthetic 39-amino-acid peptide from Eli Lilly that activates the GIP and GLP-1 receptors, and it is the active ingredient of the registered medicine Mounjaro. This hub answers the questions people ask about it from trial records and regulator documents.
Record card
| Common name | tirzepatide |
|---|---|
| Research code | LY3298176 |
| Developer | Eli Lilly |
| Structure | 39-amino-acid linear peptide with a C20 fatty diacid at position 20 |
| Receptors activated | GIP and GLP-1 |
| CAS | 2023788-19-2 |
| Australian brand name | Mounjaro (TGA register entry 23 December 2022) |
| Weight-management indication in Australia | Approved by the TGA on 9 September 2024 |
| Medicine schedule in Australia | S4, prescription medicine |
Questions answered here
06- Tirzepatide vs semaglutide: what the head-to-head trials foundTirzepatide vs semaglutide, Ozempic and Mounjaro: how the molecules differ, what two head-to-head trials found, and what the studies cannot show. Cited and dated.Updated 2026-10-14
- What is tirzepatide? Questions answered from the trial recordWhat tirzepatide is, what it is called in Australia, what the SURMOUNT-1 trial found, what adverse events and warnings are recorded, and what studies say about stopping, insulin sensitivity and dementia.Updated 2026-10-14
- Tirzepatide side effects: what trials, labels and the TGA reportThe most common tirzepatide side effects, serious risks, kidney and cancer questions, long-term trial data and Australian TGA findings, with semaglutide (Ozempic, Wegovy) side by side.Updated 2026-10-14
- How does tirzepatide work? What published studies have foundHow tirzepatide acts on GIP and GLP-1 receptors, what the approved labels list it for, and what trials found on weight, regain after stopping, and heart, sleep and liver outcomes.Updated 2026-10-14
- Is tirzepatide available in Australia? TGA status of Mounjaro, Ozempic and WegovyTirzepatide is registered in Australia as Mounjaro, a Schedule 4 prescription-only medicine. ARTG dates, Ozempic and Wegovy indications, US DailyMed labels and sport rules.Updated 2026-10-14
- Tirzepatide half-life: how long does it stay in the body?What the Mounjaro label and human pharmacokinetic studies report about tirzepatide, and the limits of those measurements.Updated 2026-10-14
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