Compound hub
Ipamorelin
Ipamorelin is a synthetic peptide of five amino acids that activates the ghrelin receptor and was first described by Novo Nordisk researchers in 1998 (Raun et al., 1998); an FDA review dated 19 August 2024 found it is not a component of any FDA-approved drug. This hub answers the questions people ask about it from published studies and official records.
Record card
| Common name | ipamorelin |
|---|---|
| Research code | NNC 26-0161 (Johansen et al., 1998) |
| Structure | Pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Formula and weight | C38H49N9O5; 711.9 g/mol |
| CAS | 170851-70-4 |
| Origin paper | Raun et al., European Journal of Endocrinology, 1998 |
| Australian status as of 14 October 2026 | Schedule 4 and Appendix D, October 2026 Poisons Standard |
| Approved medicine containing it | None found in the FDA review, 19 August 2024 |
Questions answered here
04- What is ipamorelin? What published studies say it does in the bodyIpamorelin is a five-amino-acid peptide that activates the ghrelin receptor. What rat, mouse, pig and human studies found, and what they did not. Research material is not a medicine.Updated 2026-10-14
- Tesamorelin vs ipamorelin, and how sermorelin, GHRP-6, hexarelin and MK-677 differIpamorelin copies ghrelin. Tesamorelin and sermorelin copy GHRH. GHRP-6, hexarelin and MK-677 are older ghrelin-receptor compounds. What published studies and regulators record for each, and which comparisons were not found in the searches for this page.Updated 2026-10-14
- Is ipamorelin legal in Australia? Poisons Standard, TGA, FDA and WADA recordsIpamorelin is a Schedule 4 substance in Australia and is also listed in Appendix D, clause 5, of the October 2026 Poisons Standard. What the TGA, FDA and WADA records say, with dates.Updated 2026-10-14
- Ipamorelin side effects: what the trials, the FDA and the TGA recordedThe quantified trial adverse-event data found for ipamorelin come from one small bowel-surgery trial; regulator reviews also describe individual reports. What the FDA, the TGA and PubMed records say, and what they do not cover.Updated 2026-10-14
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