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Compound hub

GHRP-2 and GHRP-6

GHRP-2 (also called pralmorelin) and GHRP-6 are two lab-made peptides, each a short chain of six amino acids. Both act on the body's ghrelin receptor and prompt the release of growth hormone. This hub explains them in plain English, using journal papers, a Japanese drug label, regulator records and sport rules. It also says clearly where no human study exists.

Articles 5Updated 2026-10-16

Record card

Record card for GHRP-2 and GHRP-6
Common namesGHRP-2 (pralmorelin) and GHRP-6
ClassGrowth hormone secretagogues: synthetic hexapeptides (six amino acids each) that act at the ghrelin receptor
GHRP-6 sequenceHis-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (Bowers et al., 1992)
GHRP-2 sequenceNot taken from an opened paper for this hub, so it is not printed here
GHRP-6 serum half-life in men20 minutes for immunoreactive GHRP (Bowers et al., 1992)
Pralmorelin terminal half-life, 18 healthy menAbout 0.42 to 0.69 hours after intravenous administration (Japanese prescribing information, revised July 2022)
Approved use of pralmorelinA diagnostic for growth hormone secretion failure in Japan; sales began February 2005 (Japanese prescribing information)
Poisons Standard, October 2026Individual Schedule 4 entries for both, each also in Appendix D, clause 5 (F2026L01327)
FDA 503B bulks listCategory 2: GHRP-2 (two named routes) and GHRP-6 (FDA list, updated 21 March 2025)
WADA 2026 Prohibited ListNamed at S2.2.4; prohibited at all times

Questions answered here

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  1. GHRP-2 and GHRP-6 side effects: what the Japanese label, the FDA and the TGA recordWhat is recorded about GHRP-2 (pralmorelin) and GHRP-6 safety: the Japanese diagnostic label's adverse reactions and class warning, the FDA 503B category 2 listing, and the gaps. Records only; not medical advice.Updated 2026-10-16
  2. GHRP-2 and GHRP-6 study findings: what the research measured, and what it did notWhat human studies of GHRP-2 (pralmorelin) and GHRP-6 measured: growth hormone release, a Japanese diagnostic approval and a one-volunteer urine study. No body-composition outcome trial was opened.Updated 2026-10-16
  3. How do GHRP-2 and GHRP-6 work? The ghrelin receptor and what the studies measuredHow GHRP-2 and GHRP-6 act on the ghrelin receptor to release growth hormone, what Bowers and colleagues measured in 1992, the 20-minute GHRP-6 half-life, and the pralmorelin half-life range from the Japanese label.Updated 2026-10-16
  4. Is GHRP-6 legal in Australia? Poisons Standard, TGA, FDA and WADA records for GHRP-2 and GHRP-6What the October 2026 Poisons Standard, the TGA, the FDA and WADA record about GHRP-2 (pralmorelin) and GHRP-6, with sources and check dates. Records only; this is not legal advice.Updated 2026-10-16
  5. What are GHRP-2 and GHRP-6? Two growth hormone secretagogues explainedWhat GHRP-2 (pralmorelin) and GHRP-6 are: synthetic six-amino-acid peptides that act on the ghrelin receptor, and how they differ from growth hormone and from growth hormone-releasing hormone.Updated 2026-10-16

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