Compound hub
Tesamorelin
Tesamorelin is a synthetic 44-amino-acid copy of growth-hormone-releasing hormone with a hexenoyl group at one end, and the FDA approved it in 2010 as Egrifta for excess abdominal fat in adults with HIV and lipodystrophy. This hub answers the questions people ask about it from FDA labels, published trials and regulator records.
Record card
| Common name | tesamorelin |
|---|---|
| Structure | 44-amino-acid human GRF sequence plus an N-terminal hexenoyl group (FDA Egrifta SV label, section 11) |
| US brand names | Egrifta SV and Egrifta WR (Theratechnologies Inc.) |
| US-approved use | Reduction of excess abdominal fat in HIV-infected adults with lipodystrophy; first approved 2010 |
| Label half-life | 8 minutes (Egrifta SV) in healthy subjects |
| ARTG keyword search, 14 October 2026 | No matching results for 'tesamorelin' or 'Egrifta' |
| Poisons Standard status | Held: stated on no page, in either direction |
| WADA 2026 Prohibited List | Class S2.2.4, prohibited at all times |
Questions answered here
04- Tesamorelin side effects: what the FDA label and trials reportTesamorelin side effects from the FDA Egrifta SV label and published trials: common events, warnings, heart, liver, hormones, what happened after stopping, and what is not known.Updated 2026-10-14
- What does tesamorelin do? What published studies foundWhat published studies found about tesamorelin: growth-hormone signalling, visceral fat, weight, muscle, fat returning after stopping, and what has not been tested.Updated 2026-10-14
- Tesamorelin vs sermorelin: what the records compareTesamorelin and sermorelin compared from FDA records and a 2026 review: structure, approvals, half-life, evidence tiers, hexarelin, steroids and why these records do not support a ranking.Updated 2026-10-14
- Is tesamorelin legal in Australia? ARTG, TGA, FDA and WADA recordsTesamorelin in Australia: the ARTG search result, the TGA's position, the FDA approval and label facts, and the WADA 2026 listing, each with its check date.Updated 2026-10-14
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